The newly-crowned Premiership champions go into the Stamford Bridge clash buoyed by the knowledge that the result is inconsequential.
Winning the title with two games to spare gives United the added luxury of being able to focus on the looming FA Cup Final against Jose Mourinho's side.
Ronaldo told MUTV: "Now that we are champions, there will be no pressure when we go to Chelsea so we'll enjoy the game.
"The only pressure now is for the FA Cup final. We have a great chance to win the Double. Everybody in the dressing room has worked for this and wants to win it. Then we can go on holiday and rest after a great season."
Arguably the star of United's triumphant campaign, Ronaldo admits he is delighted that the club's hard work has yielded rewards.
To be champions now, after ten months of work, is amazing," he said. "Everyone at the club is very happy, the staff, the players... everyone. I am very proud. I feel great.
"I was at home on Sunday, watching the Arsenal-Chelsea game with my friends and family. It was very exciting. I was very nervous during the game but afterwards I opened a bottle with my friends. I called some of the players to ask what we should do, then everyone met up and it was a great night.
"This feeling, this experience of being champions in England is amazing and we want to win it again next season."